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Case Management: Cutaneous Melanoma of the Head and Neck
Contributing Author: Cecelia Schmalbach, MD, MSc Jun 2017

The incidence of melanoma in the United States continues to rise, with nearly 90,000 new cases projected for 2017, 25 percent of which will occur in people younger than 40 years. Melanoma accounts for just one percent of all skin cancer diagnoses but is the primary cause of skin cancer mortality, responsible for almost 10,000 US deaths annually. Although melanoma can arise de novo, approximately half of all cases develop from a preexisting pigmented lesion. Read the full story & the medicine behind it.

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Case Management: Atrial Fibrillation
Contributing Author: Gopi Dandamudi, MD Mar 2017

AF is the most common sustained cardiac arrhythmia, affecting an estimated 2.7 to 6.1 million people in the United States, or approximately two percent of individuals <65 years and nine percent of those ≥65 years. Aside from increasing age and family history, hypertension is the greatest risk factor for AF, accounting for more than one-fifth of all cases. Read the full story & the medicine behind it.

Case Management: Treatment Options for Localized Prostate Cancer
Contributing Author: Michael Koch, MD Jan 2017

Prostate cancer is the most common noncutaneous cancer among US males.1 In 2016, nearly 181,000 new cases were diagnosed, and more than 26,000 men died from the disease. The strongest risk factors are age (rates increase until age 70 and decline thereafter), positive family history (having an affected first-degree relative elevates risk two-fold), and black race. Read the full story & the medicine behind it.

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Case Management: Endoscopic Diagnosis, Treatment, and Surveillance of Barrett's Esophagus
Contributing Authors: William Kessler, MD, Hala Fatima, MD Jan 2017

An estimated six percent of US adults have BE,1 a condition in which metaplastic columnar mucosa replaces the stratified esophageal squamous epithelium.2 Metaplasia is often a response to chronic inflammation, with GERD linked to a 10 to 15 percent risk. Other risk factors for BE include hiatal hernia, age >50 years, male gender, white race, cigarette smoking, family history, and central obesity. Read the full story & the medicine behind it.