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Case Management: Treatment Options for Localized Prostate Cancer
Contributing Author: Michael Koch, MD Jan 2017

Prostate cancer is the most common noncutaneous cancer among US males.1 In 2016, nearly 181,000 new cases were diagnosed, and more than 26,000 men died from the disease. The strongest risk factors are age (rates increase until age 70 and decline thereafter), positive family history (having an affected first-degree relative elevates risk two-fold), and black race. Read the full story & the medicine behind it.

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Case Management: Endoscopic Diagnosis, Treatment, and Surveillance of Barrett's Esophagus
Contributing Authors: William Kessler, MD, Hala Fatima, MD Jan 2017

An estimated six percent of US adults have BE,1 a condition in which metaplastic columnar mucosa replaces the stratified esophageal squamous epithelium.2 Metaplasia is often a response to chronic inflammation, with GERD linked to a 10 to 15 percent risk. Other risk factors for BE include hiatal hernia, age >50 years, male gender, white race, cigarette smoking, family history, and central obesity. Read the full story & the medicine behind it.

Case Management: Abdominal Aortic Aneurysm
Contributing Author: Andres Fajardo, MD Jun 2016

AAA is a degenerative process occurring between the diaphragm and the aortic bifurcation that results in a segmental, full-thickness dilatation of the abdominal aorta exceeding the normal vessel diameter by 50 percent (i.e., ≥3.0 cm). AAAs, approximately 85 percent of which are infrarenal, are usually asymptomatic until they rupture, an often fatal event with a mortality of 85 to 90 percent. Of those patients who reach the hospital, only 50 to 70 percent survive. Read the full story & the medicine behind it.

Case Management: Using Precision Medicine to Personalize Cancer Treatment
Contributing Author: Milan Radovich, PhD Dec 2015

ATC is a rare form of undifferentiated cancer that accounts for less than two percent of all thyroid cancers but has a disproportionately high mortality rate of 33 to 50 percent. Patients are usually in their sixth or seventh decade of life at presentation, have an average median survival of five months, and fewer than 20 percent are alive one year after diagnosis. Read the full story & the medicine behind it.