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Case Management: Treatment of Brain Metastases
Contributing Author: Kevin McMullen, MD Jul 2015

Brain metastases are the most common intracranial lesions in adults, accounting for more than half of all brain tumors and developing in 10 to 30 percent of adults with systemic malignancies. Moreover, the incidence of brain metastases may be increasing, owing to improved detection of small lesions by MRI and enhanced control of extracranial disease. Read the full story & the medicine behind it.

Case Management: Treatment of Achalasia
Contributing Author: John DeWitt, MD Apr 2015

Achalasia is a primary motility disorder characterized by the absence of esophageal body peristalsis, elevated lower esophageal sphincter (LES) pressure, and impaired LES relaxation during swallowing that collectively combine to prevent passage of bolus through the gastroesophageal junction (GEJ). Read the full story & the medicine behind it.

Case Management: Making Lung Transplantation Available to More Patients
Contributing Author: Thomas Wozniak, MD Jan 2015

The first human lung transplant was performed in 1963, with the recipient surviving for 18 days before succumbing to renal failure and malnutrition. Although this operation established the technical feasibility of lung transplantation, few others were per formed until the mid-1980s, when advances in surgical techniques and the advent of cyclosporine immunosuppression made transplantation an accepted option for end-stage lung disease. Read the full story & the medicine behind it.